RAD51C NM_058216.3(RAD51C):c.870T>A (p.Ile290=)

CI-VAR-00030666Explore in graph →p.Ile290=NM_058216.3:c.870T>AClinVar 184581 rs376402418

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
184581	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Hereditary cancer-predisposing syndrome; Fanconi anemia complementation group O; Hereditary breast ovarian cancer syndrome; Malignant tumor of breast; Breast and/or ovarian cancer; Familial ovarian cancer; Breast-ovarian cancer, familial, susceptibility to, 3	germline	17	Mar 13, 2026	clinvar