CFTR NM_000492.4(CFTR):c.1210-11T>G

CI-VAR-00025746Explore in graph →NM_000492.4:c.1210-11T>GClinVar 178713 rs73715573

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
178713	Pathogenic/Likely pathogenic; other	criteria provided, multiple submitters, no conflicts	2	Congenital bilateral aplasia of vas deferens from CFTR mutation; Cystic fibrosis; Lung cancer; Cervical cancer; Familial cancer of breast; Bronchiectasis with or without elevated sweat chloride 1; Hereditary pancreatitis; Sarcoma; Malignant tumor of esophagus; Cholangiocarcinoma; Nonpapillary renal cell carcinoma; Uterine corpus endometrial carcinoma; Familial pancreatic carcinoma; Malignant lymphoma, large B-cell, diffuse; Fetal anomalies with a likely genetic cause	germline	28	Jul 22, 2026	clinvar