Variant · Deletion

NF2 NC_000022.11:g.29602212_29610711del

CI-VAR-00240187Explore in graph →ClinVar 1691507

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1691507	Pathogenic	criteria provided, single submitter	1	Neurofibromatosis, type 2	germline	1	Mar 21, 2022	clinvar

Nomenclature

Record

Gene: NF2
Type: Deletion
HGVS g.: NC_000022.11:g.29602212_29610711del
Assembly: GRCh38
Position: chr22:29602211-29610711
Ref / Alt: GTGGTGGCGGGTGCCTGTAATCCCAACTACTGGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGAGGTTGCAGAGAGCCGAGACCGCCCCATTGTACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTCTCAAAACAAAAAACAAACGAAAAAACACAGTAAATTGTCCCTATTTGACTACTAAGAGCTATTTTAAAATAGAATTTATTATCTAAGTACAGAAAGGTGTAATTATCCCCCCTACACCCGTTAGAACCCTTGATGACACTAAATAAATAATACATGAATACGGTTCAAAAATGGGCATCATAGAGTATAAAATAAAGAATGCTTTCATTTTCAACCCAAATTCAGCAATTTCATAGGATGCCAGGCTCAGCTCTAAAGCCTTATATGTATTCAGTGCGCTGAAATTCAACAACCTCACGAGGTAGGTATAACCAATAATAATTCTAGGCGGGGCGTGGTGGCTCACGCCTGTAATCCTAGCACTTCGGGAGGCCGAGGCGGGCGGATCACCTGAGGTTCGAGACCAGCCTGACGAACATGGAGAAACCCCGTCTCTAATAAAAATACAAAATTAGCCGGGCGTGGTGACGCATACCTGTAATCCCAGCTACTCGGGAGGCTGACGCCGGAAAATCGCTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCCGTCCCAATAATAATAATAATTAATAATAATAATAATAACAATAATAATAATAATTCTAAAGGGAAGCAGAGGGATCTGGCGGGAAAGTGCCAGCAAACCTAACAGGCCTCCACAAGTGTCTTTAAAGTTTCATAGGGGTCGGTATATGTGATTAACTGCCAAAGAAGAATATTCGCCGTGTGTCCGAAACGCAGTCCCCTGGGGCGCCACACTCGGAGCCTACTTGAACCGAAGAGTCCCTCCCTGGGCCAACGAAGGACCCAATTCCCCTCGCCCCGGATCCAGCCTCTAAGTGGTTTCCCGGGTAAGGTCAGCAGAGGTCCGCCGCCTCAACCAGTCTTGTTAGAGTAGGCACAAAAGCATTCAGAGTGACTGCCACTGTAGCCACTCAACGCCGAGCCTAGGCCTGCTTTTTTTGCAGTTAGAGTGAAACTTTCCATTGGTGGAGTCACCCCAAAGGAGGCGGGACGGAGCGGGAAAGTCCTGCCTACCTTGGCCTTCCCAGCCAATCGCAGCATCTATGCGTCAGCCTCCGGTTCGGTTGCGCTGCGCGTAGTGGTCTGGGCGACCTGAGGGCGGGGCCGGGAGCAGGCCCCGGGCTGTGGGGAGGGTGCGCTTCCCGCGGGCGCGCGGAGTGAGGACGGTGACAGCCACGCGCGCGCGTACGCGCCCGATGCAGCGCGGCCCCGTGACCCTAGTCGGCCGCTGAGAGGCGCGCGGAGTCTGGGCCGCTGCCGTCTAGGGGTCCCGTCCCGAGGCGTCCCCGGCATCTCCGGCCCGAATCCCGGAGTGCCGGGTCGCGCCTGCACCGAAGGTCCCGGCTCCTGTGCCCTCCCTGCAGCCGTCAGGGCCCGTCCCCCAACTCCCCTTTCCGCTCAGGCAGGGTCCTCGCGGCCCATGCTGGCCGCTGGGGACCCGCGCAGCCCAGACCGTTCCCGGGCCGGGCAGCCGGCCACCATGGTGGCCCTGAGGCCTGTGCAGCAACTCCAGGGGGGCTAAAGGGCTCAGAGTGCAGGCCGTGGGGCGCGAGGGTCCCGGGCCTGAGCCCCGCGCCATGGCCGGGGCCATCGCTTCCCGCATGAGCTTCAGCTCTCTCAAGAGGAAGCAACCCAAGACGTTCACCGTGAGGATCGTCACCATGGACGCCGAGATGGAGTTCAATTGCGAGGTAACCGGCCGGCAGCCCCGACTGCTGCGGTGACAGTCGAGGTGGAAGCTCGAGAGGTTCTCTTTATATCATCTTATGGGTGTAGCTAGAGACGGGCAGAACCGGAAGGGCCAACTAGGCCCAAAACCTCATGTTAAAGATGATTGCTGCTTTTTTTCATAGGACTTTTGGGTTTTGGCATTTCCTGAAGGTTATTTTCATTCATTGTTATTGGAAGAAGCTGGATGCTCCTGTGATAGAAAATTCAGGATTTCAGTGTCAGGCTTAAGTTAGGCTTACGCTTAAAAGCTTGAAAGTTTATTCTTTCATTAGGTAATATTGTTATGTACCCAGGTATTAGAAGTTGCGTCTTGTTTATTGGAAAGCCAATACTTGTTTCCCTTTTCTAAAGCTTGCATATTCTGGGAAAAAAAACCCTTTGAAGAACGATATAACATCTCATACTTACTTTCCACATAGTTTCCAACATGATGATAACAGCTATCAATTGTTCAGTATTTTCAAAGTGCTAGACATTTGCACATTTAATCCTCAGAACAAACCCATTTATCTAGTAAATGGCAAGGTGGGGTTTTGAACCAAGCTCACAGCCCGTACAGTACTGCTTCTCAAGTAATTTAAGTTCTTGCTGCTAAAAGTGTGGTTTGTGGACCAGCAGCATTGGCAGCAGTAAGCAAGGGTTGGCATGCTTTTTCTGTACAGGACCACATAGTAAATATTTTCAACTTTGTAGACTAGAGAATCTCTGTTGGAGTTATTCAACTCTTCAACTCTACCATTGTAACACAAAAGCAGCCTTAGATAAGATCAGCTTCCAGCATGACAGCTTAAGGAACCCATTCCTCTGTAAAACTGGTGAAAATTCTTTTTTGTTTTGTTTCGTTTTGAGACAGAATCTCACTCTGTCACCGAGGCTGGCATGCAGTAGTGTGATCATGGCTTACTGCAACCCTGACCAACCTCCCTGGCTCAATCAGTCCTCCTGCCTCAGCCTCTCGAGTAGCTGGGACCACAGGCGTGTGCCACCACACCTGGCTAATTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGAGTGCACCGGGCTAGAGTGCAATGGCGCGATCTTGTCTCACTGCCACCTCCACTTCCAGGTTCAAGTGATTCTCCTGCTTCAGCCTTCCAGGTAGCTGGGATTACAGGCGTGCGCCACCTCGTCTGGCTAATTTTTCTATTTTTAGTAGAGACAGGGTTTCACCATATTGGGCAGGCTGATCTCGAACTCCTGACCTCGTGACCAGCCGACCTGGGCCTCCCAAAGTGGTGGGAAAGTGGTGCGATTACAGATGTGAGCCACCCCGCCCAGCCTCACCTAGCTAATTTTTGTAAAGACAGGGTTTTGCCATGTTGCCCAGGCTGATCTTGAACTCCTGAGCTCAAGCAATCCACTCGCCTTGGCCTCCCAAAGTGATGGGATTACAGATGCAGCCACCACGCCTGGCCCAAAAATTCTTTTTTTAAAATCAACTATTTAAACCCTCCGGCAATGGTCCTGAGGGCAAACAACAAATGAAAAAACACCTATTCAAGAAAATCTACAAATTCGGTAAGAAAGATGAGAGGGTATGGTATTTGAACCAAGATCATTCCCTCCTTACTCACTCCTAGCTTAGTGAGGTGGAGCTTCTACTCCAGACTATTGCAAACTGTAATACCGGGCACTGCTCCCCCAGCTCCCAATCAAATGCTTTCTTCCCAGGAAAAGCAGGACATCAGCATTTCTCATCCTACCTAGAGCTACTTGTTGCTGAGGTTAAAACCTGTGTGAGTGCAATTGAAAGTTGGAGCTCTCTTTTTTTTTCTTTTGAGACGGAGTTTTGCTCTTGTTGCTCAAACTGGAGTGCAATGGTGTGATCTCGCCTCACCGCAGCCTCTGCTTCCCGGGTTCAAGCGATTCTCCCACATCAGCCTCCCAAGTAGCTGGGATTGCAGGCTTGCGCCACCATGTCTGGCTAATTTTGTATTTTTAGTAGAGGCAGGGTTTCTCCATGTTGGTCAGGCTGGTCTTGAACTCCCTACCTCAGGTGATCCACCTGCCTCGGCCTCCCAAAGTGTTGGGATTATAGGCGTGAGCCACTGTGCCCTGCGAAAAGTTGGAGCTCCCTTCTTCCACCTAGTCCCTACTTGTGGAACAGGACTGTACCTTGGACATGACATACTGAAATTACTGGTGCCCCAATTGCTCATCCCCCAGTTCTTGCAGGCTGAGCCTCAGGTTATTGCGGTCCCCTGCCTCCTTCCACCAAGTGCTCAGTTCCTAGAGTGAGGGTATTTCTCAGAGAGAATCTTTCCAGGGTCCTTCCCCACAGCTCCAGAGCCTTGGCTCCGGGATTTTGCCTCAGGAGAGAAGCAGGCCCTAAAACAGATAGCTCCTAATCTCTTTCCAATGGCAGTGACTTCATTTGCAACACAGTGTGGAGAAATTCATGCCTAAGGGCAATCTGGAGATGTGAAGGTTTTGGTAAGAGGCAACTGGGAGATCTGCGGATTTAATGGAGATGCAGCCTAGACTGTAGGCCTCCTGGTTTGCTGGAAAGAATTGGGGAATAAGACAGCTGGAAGAAGCCATTCTAGGATCAGAAGAAGGATCAAACATTGACCGCAGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCAGATCATCTGAGGTCGGGAGTTTGAGACCAGCTTGACCAATATGGTGAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGCATGGGGGCATACACTTGTAATCCCAGCTACTTGGGAGGCTGAAGCAGGAAAATCACGTGAACTGGGAGGTGGAAGTTGCAGTGAGCCAAGATCACGCCACTGCACTCCAGCCTGGGTGACAGTGAAGCTCTGTCCTGTCACAAAACAAAACATTGACCACAGACCTCTGAGGTGGTGGATGTCCCTCCTGTCCTGGTTGTATCATTATACATTGTATATTAATGTATCGAAATACTACAGGTACCCCCAACATGTGTACAACTATTATGAATCAATAAAAAACAATTTGAAAAGTAAGGTATGTGGCAGAGGTGGAAAAAAATGCTTTCCTCCAAACAGCCACAATTTGATTGTATCAGTTTGTAGAGTAAGAGCAAGTTATGCCTCAGTGTGTTGTTGAAAATAATAGAACAATATGCCACAATTAGTGGAGCTTCATAGCTGGGTGTGGTCAAGGAGAGAATAGAAGAGAACCCTACCAAAACCACTGTCATCCCAGGGTGACTGTGAGCATACCCAAAGCTGCACCTCCCTGAAGAGCAATATCATAGGCCTTAACACTTTTCAGGGGAAATGGATTTCACTCAAATAATCCAGCCAGTCGCTAAACAAATAAATAACAATTGGCCCTGGAGAGGGGGTACCAATCCCCAGAGTTGCTACAGTATATTATCTAAAATGTCCAGTTTCCAACAAGAAATTGTGAGACGTACAAAGAAACAGGAAAATATGACACATACACTGGAAAAAAGCTGGCAGCAGCAACTGCCTGTGAGACAAGGGGCCAAATTAATGAAAAAGGCTTCAAACTGGCCTATATATATATTCACAGTACTATATATATTCACAATACTAAAGGAAAATATGATGACAAAGAAGTAAAGGATGGTATGACACTGTTGCATCAATTAAAGAATATCCATAAAGATATAGAAATTATAAAAAAAGAATCAAATGAAAATTCTGGAGTTGAAAGTACAATAACAGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACATGGTAAAACCCCGTCTCTGCTAAAAATACAAAAATTAGCCAGGCGTGGTGGCCGGCACCTGTAGTCCCAGCTACGCGGGAGGCTGAGGCAGGAGAATTCCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGAGCCACTGCACACCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAGTACAATAACAAATTTAAAAATTAACTAGAGGGACTCAGGACTCAATAACAGATTTGAACTGGGTGAAGAAAGAATTCGTTAATTTTTTTTTTCTTTTTGAGACAGAGTCTCGCTCTGTTGCCTAGGCTGGAGTGCAGTGGGGCAATCTCGGCTCACTGCAACCTCTGCCTCCCTGGTTCAAGCGATTCTCCTGCCTCAGCCACCGCACAGTGGCTTTGGGAGTACTCTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACAAAAATACAAAAATTTAGTTGGGCATGATGGCGGGTGCCTGTAACCCCAGCTACTTGGGAGGTTGAGGCGGGAGAATTGCTTGAACCCGGGAGGCGGAGGTTGTAGTGAGCAGAGATCGTGCCACTGCCCTCCAACCTGGGTGACAGAGCGAGACTCCATCCCTGCCCTGAAAAAAAAAAAAAAGATGTGAAACACATACAAAAAAAAGTAAAATGGCAGTTGAATGCCAAGTAATTAGATAACTTCAATAAAATGGACAAACTCCTAGAAAGATATAAACCACCAAAATTGACCCAAGAAGAGACACTATCTGAATAGACCTATAACAAGTAAAGATATTAAATTAGTAATTGAGGGGACTCGTGGGGTAACTTGCCCTTGGGAACCAGTAGTATGGCATCGGGCTGCAAGATTGGCCTGTCCATCCTCAATGCTACCTGGCCAATTTAGGGGCCCAGTGCCTCTGGATGCTAGACTCTGGGGTCGATTATCTCCACCGGAATGTAATGGATGAACATGCATGTGATGGTGTCCAAGCCAGAACAGTGGGTAAAGCCAATGGCTATAAGAGGAGCCAATCAGTACATCTTTCATCTCGAGGAAACTGAGAACCCAGGGGCTTTGATTAAAGACATTCAGGAGAATGGGATGAAGGTTGGCCTTGCCATAAAACCAGGAACCTCAGTTCAGTATTTGGCACCATGGGCTAATCAACTAGGTATGACCTTGGTTATGACAGTGGAACCAGGGTTTGGAGGGCATAAATTCATGGAAGATATGATGTTAAAGGTTCACTGGTTGAGGATCCAGTTCCCATCTTTGGCTATAGAGGTCGCTGGTGGAATAGATCCTGACACTGTCCATAGGTGTGCAGAGGCGAAGCTAACATGATTGTGTCTGGCAGTGCTATGGTGAGGAGTGAAGACCCTAGATCTGTGATCAGCCTGTTAAGAAACATTTGCTCAGAAGCTGCTCAGAAAGATTCTCTTGATTGATGAAACCTTAAGGAGCCCAATGTTTGTTTATGAAATCTCCTTTTTACTGGAAAACAGGAATATTGACTACCAAATCATAGTGTAGTTGAAGCCATTCTGCGTTTTTGAGCAGTTATTCGTTTCAGTGATTATAATTGATTGTGCAGAGTATTCTAAGAAGTTAGAAATTGGTGTGTATAACTACATTTTCAGTGATGCAATTTAATGATTAGTGAGTGAGATACTGTTTTTATTGAGAGCCTTGATTTTTATAAAGAGTAAAAATATGGCTGCATTAAGGGTACAAACAGAAAAGTGTCTTAATGTCTAAGGAGGGCATATTAGCTACACTATAAAAACAATTTTTTTCTGTATTTCTGAAAAGAATTTTGTTGTTTCTCAGTTGTTTTCCAAAAGCAAAGGAAGTCTTAATGTTTTTTTCTATTTCGTGTTATGTGTGATTTGTTTATATGCTTGGTAATATGAGTCTAATGGAATTTAAAAATATAAGTTTGGGTAGGATAGTATACCCTTAAAAAATAAATAAATAATTAGAGAGAGAGAGAGAGAGAGAGACCTGGGCACAGTGGCTGTTGCCTGTAATCTCAGCACTTTGGGAGGTCAAGGCAGGAGGATCCTTTGAGGCCAGGAGCTTGAGACCAACCTGGGCAACATAGAGAGACCCCAACTCTAAAATATACATACTATATCTAAACTCAGCTAGGCGTGGTGGTGTGAGCCTGGAGTCCCAGCTACTCAGGAGGTTAAGGTGTGAGGATCACTTGATCCCAGGAGGTTGAGGAGGCAGTGAGCTATGATTGTGCCACAGTGCTTCAGCCAGGGTGACAGAGTGAGACCCTGTCTCTTAAAAAAAAGAAAAGAGGCTGGGTGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAAGCCAAGGTGGGCAGATCACGAGGTCAGGAGTTCAAGACCAGCCTGTCTAATATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGAGCATGGTGGAGTGCGCCTGTAGTCCCAGCTACTCGAGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAAGTTGGAGGTTGCAGTGAGCTGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAAAGTGAGACTCCATCTCAAAAAAAAAAAAAAAGAAGAAAGAAAAGCAAAGCAAAGCCCAGGCCTGTACCTACTAGAGGTCCTGAT 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