Variant · Snv
TLE2 NM_003260.5(TLE2):c.946G>A (p.Gly316Arg)
CI-VAR-00239736Explore in graph →p.Gly316ArgNM_003260.5:c.946G>AClinVar 1679861 rs201317355
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1679861 | Likely benign | criteria provided, single submitter | 1 | Decreased total neutrophil count; Decreased total lymphocyte count; Clear cell carcinoma of kidney; Malignant tumor of esophagus; Lung cancer; Ovarian serous cystadenocarcinoma; Gastric cancer; Hepatocellular carcinoma | germline | 3 | — | clinvar |