SDHC NM_003001.5(SDHC):c.354T>C (p.Phe118=)

CI-VAR-00025714Explore in graph →p.Phe118=NM_003001.5:c.354T>CClinVar 165182 rs61733156

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
165182	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Hereditary cancer-predisposing syndrome; Pheochromocytoma/paraganglioma syndrome 3; Gastrointestinal stromal tumor; SDHC-related disorder; Hereditary pheochromocytoma and paraganglioma; Cowden syndrome	germline	17	Feb 03, 2026	clinvar