PLEKHG2 NM_022835.3(PLEKHG2):c.995G>T (p.Gly332Val)

CI-VAR-00233934Explore in graph →p.Gly332ValNM_022835.3:c.995G>TClinVar 1601166 rs117405645

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1601166	Benign	criteria provided, multiple submitters, no conflicts	2	Leukodystrophy and acquired microcephaly with or without dystonia; Malignant tumor of esophagus; Acute myeloid leukemia; Lung cancer	germline	4	Jan 21, 2026	clinvar