SMC1A NM_006306.4(SMC1A):c.2350A>G (p.Ile784Val)

CI-VAR-00025195Explore in graph →p.Ile784ValNM_006306.4:c.2350A>GClinVar 159949 rs587784411

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
159949	Uncertain significance	criteria provided, multiple submitters, no conflicts	2	Congenital muscular hypertrophy-cerebral syndrome; Nonpapillary renal cell carcinoma; Inborn genetic diseases	germline	3	May 13, 2025	clinvar