Variant · Snv
CCDC88C NM_001080414.4(CCDC88C):c.4975C>A (p.Arg1659=)
CI-VAR-00025094Explore in graph →p.Arg1659=NM_001080414.4:c.4975C>AClinVar 158114 rs150512553
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 158114 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Spinocerebellar ataxia type 40; Hydrocephalus, nonsyndromic, autosomal recessive 1; Colon adenocarcinoma; Gastric cancer; Familial cancer of breast; Sarcoma; Thymoma; Nonpapillary renal cell carcinoma; Uveal melanoma; Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Hepatocellular carcinoma; Malignant tumor of esophagus | germline | 6 | Feb 04, 2026 | clinvar |