HNF1A NM_000545.8(HNF1A):c.815G>A (p.Arg272His)

CI-VAR-00006334Explore in graph →p.Arg272HisNM_000545.8:c.815G>AClinVar 14931 rs137853238

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
14931	Pathogenic	reviewed by expert panel	3	Type 1 diabetes mellitus 20; Monogenic diabetes; Maturity-onset diabetes of the young; Maturity-onset diabetes of the young type 3; HNF1A-related disorder; Hepatic adenomas, familial; HNF1A-related disorders	germline	14	Jul 05, 2022	clinvar