TMEM231 NM_001077418.3(TMEM231):c.582+1G>A

CI-VAR-00216629Explore in graph →NM_001077418.3:c.582+1G>AClinVar 1454613 rs752141701

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1454613	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Joubert syndrome 20; Meckel syndrome, type 11; TMEM231-related disorder; Squamous cell carcinoma of the head and neck; Ciliopathy; Pancreatic adenocarcinoma	germline	7	Feb 10, 2026	clinvar