SDHAF2 NM_017841.4(SDHAF2):c.229_230del (p.Arg77fs)

CI-VAR-00206978Explore in graph →p.Arg77fsNM_017841.4:c.229_230delClinVar 1452374 rs1336819076

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1452374	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Hereditary pheochromocytoma and paraganglioma; Pheochromocytoma/paraganglioma syndrome 2; Hereditary cancer-predisposing syndrome; Inherited phaeochromocytoma and paraganglioma excluding NF1	germline	6	Apr 22, 2026	clinvar