RET NM_020975.6(RET):c.3217_3218dup (p.Ser1073fs)

CI-VAR-00222339Explore in graph →p.Ser1073fsNM_020975.6:c.3217_3218dupClinVar 1433312 rs1428704590

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1433312	Uncertain significance	criteria provided, multiple submitters, no conflicts	2	Multiple endocrine neoplasia, type 2; Hereditary cancer-predisposing syndrome; Pheochromocytoma; Multiple endocrine neoplasia type 2B; Hirschsprung disease, susceptibility to, 1; Familial medullary thyroid carcinoma; Multiple endocrine neoplasia type 2A	germline	4	Jan 16, 2026	clinvar