SDHA NM_004168.4(SDHA):c.91C>T (p.Arg31Ter)

CI-VAR-00024395Explore in graph →p.Arg31TerNM_004168.4:c.91C>TClinVar 142601 rs142441643

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
142601	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Hereditary cancer-predisposing syndrome; Carney triad; Pheochromocytoma/paraganglioma syndrome 5; Pilocytic astrocytoma; Mitochondrial complex II deficiency, nuclear type 1; Leigh syndrome; Rhabdomyosarcoma; Gastrointestinal stromal tumor; Neurodegeneration with ataxia and late-onset optic atrophy; Dilated cardiomyopathy 1GG; SDHA-related disorder; Hereditary pheochromocytoma and paraganglioma; Inherited phaeochromocytoma and paraganglioma excluding NF1; Intellectual disability	germline	52	Jun 01, 2026	clinvar