POLG NM_002693.3(POLG):c.3105-11T>C

CI-VAR-00022507Explore in graph →NM_002693.3:c.3105-11T>CClinVar 138754 rs2302084

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
138754	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Progressive sclerosing poliodystrophy; Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 1; Mitochondrial DNA depletion syndrome 4b; Sensory ataxic neuropathy, dysarthria, and ophthalmoparesis; Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 1; Hepatocellular carcinoma; Germ cell tumor of testis	germline	14	Feb 04, 2026	clinvar