Variant · Snv
OPA3 NM_025136.4(OPA3):c.-38A>G
CI-VAR-00022483Explore in graph →NM_025136.4:c.-38A>GClinVar 138572 rs45527139
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 138572 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | 3-Methylglutaconic aciduria type 3; Optic atrophy 3; Acute myeloid leukemia; Nonpapillary renal cell carcinoma; Melanoma; Malignant tumor of esophagus; Pancreatic adenocarcinoma; Sarcoma; Gastric cancer; Cervical cancer | germline | 7 | Jul 19, 2021 | clinvar |