Variant · Snv
LARS1 NM_020117.11(LARS1):c.2488-7T>G
CI-VAR-00022432Explore in graph →NM_020117.11:c.2488-7T>GClinVar 138090 rs17104268
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 138090 | Benign | criteria provided, multiple submitters, no conflicts | 2 | LARS1-related disorder; Uterine carcinosarcoma; Thymoma; Acute myeloid leukemia; Nonpapillary renal cell carcinoma; Uterine corpus endometrial carcinoma; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Familial pancreatic carcinoma; Ovarian cancer; Uveal melanoma; Lymphoma; Familial cancer of breast | germline | 4 | Feb 04, 2026 | clinvar |