Variant · Snv
GFM1 NM_024996.7(GFM1):c.1083+6T>G
CI-VAR-00022381Explore in graph →NM_024996.7:c.1083+6T>GClinVar 137461 rs142919829
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 137461 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1; Gastric cancer; Ovarian serous cystadenocarcinoma; Thymoma; Cholangiocarcinoma; Familial cancer of breast; Ovarian cancer; Clear cell carcinoma of kidney; Sarcoma; Acute myeloid leukemia; Nonpapillary renal cell carcinoma; Cervical cancer; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Familial pancreatic carcinoma; Malignant tumor of esophagus; Lung cancer | germline | 10 | Apr 01, 2026 | clinvar |