Variant · Snv
EZH2 NM_004456.5(EZH2):c.2110+6T>G
CI-VAR-00022354Explore in graph →NM_004456.5:c.2110+6T>GClinVar 137273 rs41277434
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 137273 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Weaver syndrome; Hepatocellular carcinoma; Nonpapillary renal cell carcinoma; Ovarian cancer; Uveal melanoma; Familial pancreatic carcinoma; Malignant lymphoma, large B-cell, diffuse; Sarcoma; Lymphoma; Uterine corpus endometrial carcinoma; Uterine carcinosarcoma; Cholangiocarcinoma; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Thymoma; Acute myeloid leukemia | germline | 8 | Feb 03, 2026 | clinvar |