Variant · Snv
KPNA7 NM_001145715.3(KPNA7):c.73C>T (p.Arg25Ter)
CI-VAR-00207135Explore in graph →p.Arg25TerNM_001145715.3:c.73C>TClinVar 1371946 rs571947684
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1371946 | Uncertain significance | criteria provided, multiple submitters, no conflicts | 2 | Oocyte/zygote/embryo maturation arrest 17; Familial cancer of breast | germline | 3 | Mar 21, 2022 | clinvar |