Variant · Snv
DCLRE1C NM_001033855.3(DCLRE1C):c.959C>G (p.Ser320Cys)
CI-VAR-00022336Explore in graph →p.Ser320CysNM_001033855.3:c.959C>GClinVar 137073 rs41298896
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 137073 | Benign | reviewed by expert panel | 3 | Histiocytic medullary reticulosis; Severe combined immunodeficiency due to DCLRE1C deficiency; Athabaskan severe combined immunodeficiency; Uterine corpus endometrial carcinoma; Clear cell carcinoma of kidney; Acute myeloid leukemia; Colorectal cancer; Cervical cancer | germline | 12 | Nov 14, 2023 | clinvar |