Variant · Snv
DARS2 NM_018122.5(DARS2):c.397-6T>G
CI-VAR-00022335Explore in graph →NM_018122.5:c.397-6T>GClinVar 137071 rs115051769
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 137071 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome; Familial pancreatic carcinoma; Sarcoma; Gastric cancer; Lymphoma; Malignant tumor of esophagus; Cervical cancer; Ovarian cancer; Clear cell carcinoma of kidney; Uterine carcinosarcoma; Acute myeloid leukemia; Uterine corpus endometrial carcinoma; Uveal melanoma; Ovarian serous cystadenocarcinoma; Thymoma | germline | 8 | Feb 03, 2026 | clinvar |