Variant · Snv
DARS2 NM_018122.5(DARS2):c.228-12C>G
CI-VAR-00022334Explore in graph →NM_018122.5:c.228-12C>GClinVar 137070 rs9425753
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 137070 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome; Sarcoma; Ovarian serous cystadenocarcinoma; Cervical cancer; Gastric cancer; Uterine carcinosarcoma; Lung cancer; Thymoma; Cholangiocarcinoma; Acute myeloid leukemia; Malignant tumor of esophagus; Clear cell carcinoma of kidney | germline | 11 | Jan 29, 2026 | clinvar |