Variant · Deletion
SPG7 NM_003119.4(SPG7):c.184-5_184-4del
CI-VAR-00203872Explore in graph →NM_003119.4:c.184-5_184-4delClinVar 1344130 rs5818722
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1344130 | Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Hereditary spastic paraplegia; Colon adenocarcinoma; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Malignant lymphoma, large B-cell, diffuse; Colorectal cancer | germline | 3 | Nov 27, 2024 | clinvar |