TSHR NM_000369.5(TSHR):c.692+48T>A

CI-VAR-00203791Explore in graph →NM_000369.5:c.692+48T>AClinVar 1342855 rs28516678

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1342855	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Familial hyperthyroidism due to mutations in TSH receptor; Hypothyroidism due to TSH receptor mutations; Familial gestational hyperthyroidism; Uveal melanoma; Uterine carcinosarcoma; Malignant lymphoma, large B-cell, diffuse; Thymoma	germline	3	Sep 10, 2021	clinvar