ERCC4 NM_005236.3(ERCC4):c.2579C>A (p.Ala860Asp)

CI-VAR-00021131Explore in graph →p.Ala860AspNM_005236.3:c.2579C>AClinVar 134138 rs4986933

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
134138	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Xeroderma pigmentosum, group F; Cockayne syndrome; Fanconi anemia complementation group Q; Hutchinson-Gilford syndrome; Xeroderma pigmentosum; Inborn genetic diseases; Hereditary cancer-predisposing syndrome	germline	12	Jan 31, 2026	clinvar