Variant · Snv
RPS27 NM_001030.6(RPS27):c.228A>T (p.Gly76=)
CI-VAR-00203452Explore in graph →p.Gly76=NM_001030.6:c.228A>TClinVar 1336053 rs138950537
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1336053 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Uveal melanoma; Melanoma; Hepatocellular carcinoma; Lung cancer; Cervical cancer; Clear cell carcinoma of kidney; Colon adenocarcinoma; Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Malignant tumor of esophagus; Sarcoma; Gastric cancer; Ovarian serous cystadenocarcinoma; Thymoma | germline | 6 | Feb 02, 2026 | clinvar |