FGFR2 NM_000141.5(FGFR2):c.1032G>A (p.Ala344=)

CI-VAR-00006184Explore in graph →p.Ala344=NM_000141.5:c.1032G>AClinVar 13268 rs121918491

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
13268	Pathogenic	criteria provided, multiple submitters, no conflicts	2	Crouzon syndrome; CRANIOSYNOSTOSIS, NONCLASSIFIABLE AUTOSOMAL DOMINANT; SCAPHOCEPHALY AND AXENFELD-RIEGER ANOMALY; Craniosynostosis syndrome; FGFR2-related craniosynostosis; Acrocephalosyndactyly type I; FGFR2-related disorder; Common craniosynostosis syndromes; Hepatocellular carcinoma; Pfeiffer syndrome	germline	17	Jun 12, 2026	clinvar