ZFYVE26 NM_015346.4(ZFYVE26):c.1224G>T (p.Gly408=)

CI-VAR-00020522Explore in graph →p.Gly408=NM_015346.4:c.1224G>TClinVar 130776 rs17104689

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
130776	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Hereditary spastic paraplegia 15; Spastic paraplegia; Hereditary spastic paraplegia; Hepatocellular carcinoma; Malignant tumor of esophagus; Lung cancer; Cervical cancer; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1; Thymoma; Acute myeloid leukemia; Uterine corpus endometrial carcinoma	germline	11	Jan 31, 2026	clinvar