Variant · Snv
TCOF1 NM_001371623.1(TCOF1):c.3604-3C>T
CI-VAR-00020498Explore in graph →NM_001371623.1:c.3604-3C>TClinVar 130572 rs11743855
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 130572 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Treacher Collins syndrome 1; Cholangiocarcinoma; Hepatocellular carcinoma; Nonpapillary renal cell carcinoma; Adrenocortical carcinoma, hereditary; Familial cancer of breast; Lymphoma; Thymoma; Colorectal cancer; Uterine carcinosarcoma; Ovarian cancer; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Uveal melanoma; Familial pancreatic carcinoma; Malignant lymphoma, large B-cell, diffuse | germline | 7 | Feb 03, 2026 | clinvar |