SCN9A NM_001365536.1(SCN9A):c.1155G>T (p.Val385=)

CI-VAR-00020472Explore in graph →p.Val385=NM_001365536.1:c.1155G>TClinVar 130255 rs58465962

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
130255	Benign	criteria provided, multiple submitters, no conflicts	2	Channelopathy-associated congenital insensitivity to pain, autosomal recessive; Primary erythromelalgia; Paroxysmal extreme pain disorder; Neuropathy, hereditary sensory and autonomic, type 2A; Generalized epilepsy with febrile seizures plus, type 7; Melanoma; Hepatocellular carcinoma; Acute myeloid leukemia; Cervical cancer; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1	germline	13	Feb 03, 2026	clinvar