Variant · Snv
PACS1 NM_018026.4(PACS1):c.2061T>A (p.Ser687=)
CI-VAR-00020447Explore in graph →p.Ser687=NM_018026.4:c.2061T>AClinVar 129870 rs572697
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 129870 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Schuurs-Hoeijmakers syndrome; Inborn genetic diseases; Sarcoma; Ovarian serous cystadenocarcinoma; Colorectal cancer; Gastric cancer; Thyroid cancer, nonmedullary, 1; Uterine corpus endometrial carcinoma; Clear cell carcinoma of kidney; Colon adenocarcinoma; Acute myeloid leukemia; Lung cancer; Cervical cancer | germline | 7 | Feb 03, 2026 | clinvar |