FA2H NM_024306.5(FA2H):c.229C>T (p.Leu77=)

CI-VAR-00020389Explore in graph →p.Leu77=NM_024306.5:c.229C>TClinVar 129028 rs929881

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
129028	Benign	criteria provided, multiple submitters, no conflicts	2	Hereditary spastic paraplegia 35; Spastic paraplegia; Hereditary spastic paraplegia; Familial cancer of breast	germline	15	Feb 04, 2026	clinvar