Variant · Deletion
RAD51C NM_058216.3(RAD51C):c.1026+5_1026+7del
CI-VAR-00020307Explore in graph →NM_058216.3:c.1026+5_1026+7delClinVar 128201 rs587781410
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 128201 | Pathogenic/Likely pathogenic | criteria provided, multiple submitters, no conflicts | 2 | Hereditary cancer-predisposing syndrome; Fanconi anemia complementation group O; Breast-ovarian cancer, familial, susceptibility to, 3; Hereditary site-specific ovarian cancer syndrome; Hereditary breast ovarian cancer syndrome; Breast and/or ovarian cancer; Uterine corpus cancer; Hereditary cancer; Inherited breast cancer and ovarian cancer; RAD51C-related cancer predisposition; Inherited ovarian cancer (without breast cancer); RAD51C-related disorder | germline | 30 | Mar 03, 2026 | clinvar |