CDH1 NM_004360.5(CDH1):c.1174G>A (p.Val392Ile)

CI-VAR-00020033Explore in graph →p.Val392IleNM_004360.5:c.1174G>AClinVar 127907 rs141864044

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
127907	Likely benign	reviewed by expert panel	3	Hereditary cancer-predisposing syndrome; Hereditary diffuse gastric adenocarcinoma; CDH1-related diffuse gastric and lobular breast cancer syndrome; Familial cancer of breast; Ovarian cancer	germline	12	Aug 10, 2023	clinvar