Variant · Snv
TBC1D8B NM_017752.3(TBC1D8B):c.1407A>G (p.Gly469=)
CI-VAR-00200390Explore in graph →p.Gly469=NM_017752.3:c.1407A>GClinVar 1268489 rs73531168
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1268489 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Gastric cancer; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1; Nonpapillary renal cell carcinoma; Sarcoma; Lung cancer; Clear cell carcinoma of kidney; Cervical cancer | germline | 5 | Feb 01, 2026 | clinvar |