ESR1 NM_000125.4(ESR1):c.1782G>A (p.Thr594=)

CI-VAR-00200181Explore in graph →p.Thr594=NM_000125.4:c.1782G>AClinVar 1263746 rs2228480

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1263746	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Migraine with or without aura, susceptibility to; Familial cancer of breast; Estrogen resistance syndrome; Myocardial infarction, susceptibility to; Migraine with or without aura, susceptibility to, 1; ESR1-related disorder	germline	4	Mar 23, 2022	clinvar