TGFB1 NM_000660.7(TGFB1):c.29C>T (p.Pro10Leu)

CI-VAR-00006070Explore in graph →p.Pro10LeuNM_000660.7:c.29C>TClinVar 12534 rs1800470

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
12534	Benign	criteria provided, multiple submitters, no conflicts	2	Breast cancer, invasive, susceptibility to; Cystic fibrosis; Inflammatory bowel disease, immunodeficiency, and encephalopathy; Diaphyseal dysplasia; Meckel syndrome, type 10	germline	11	Feb 04, 2026	clinvar