Variant · Snv
CLCN2 NM_004366.6(CLCN2):c.1101G>A (p.Pro367=)
CI-VAR-00198900Explore in graph →p.Pro367=NM_004366.6:c.1101G>AClinVar 1224803 rs3749221
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1224803 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Chronic lymphocytic leukemia/small lymphocytic lymphoma; Lymphoma; Thyroid cancer, nonmedullary, 1; Lung cancer; Uveal melanoma; Familial pancreatic carcinoma; Colon adenocarcinoma; Colorectal cancer; Melanoma; Cholangiocarcinoma; Acute myeloid leukemia; Hepatocellular carcinoma; Nonpapillary renal cell carcinoma; Uterine corpus endometrial carcinoma; Clear cell carcinoma of kidney; Sarcoma; Thymoma; Adrenocortical carcinoma, hereditary; Ovarian cancer | germline | 6 | Jan 27, 2026 | clinvar |