Variant · Snv
POLR1B NM_019014.6(POLR1B):c.493-17A>G
CI-VAR-00198716Explore in graph →NM_019014.6:c.493-17A>GClinVar 1220927 rs62158585
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1220927 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Uveal melanoma; Malignant lymphoma, large B-cell, diffuse; Uterine carcinosarcoma; Cholangiocarcinoma; Hepatocellular carcinoma | germline | 3 | May 14, 2021 | clinvar |