FLNA NM_001110556.2(FLNA):c.620C>T (p.Pro207Leu)

CI-VAR-00005980Explore in graph →p.Pro207LeuNM_001110556.2:c.620C>TClinVar 11755 rs28935469

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
11755	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Oto-palato-digital syndrome, type I; Short stature; Conductive hearing impairment; Cleft palate; Familial thoracic aortic aneurysm and aortic dissection; Oto-palato-digital syndrome, type II; Melnick-Needles syndrome; Heterotopia, periventricular, X-linked dominant; Frontometaphyseal dysplasia; FLNA-related disorder; Gastric cancer; Thyroid cancer, nonmedullary, 1	germline	11	May 11, 2025	clinvar