SEC61A1 NM_013336.4(SEC61A1):c.784C>A (p.Arg262=)

CI-VAR-00196077Explore in graph →p.Arg262=NM_013336.4:c.784C>AClinVar 1170774 rs144643278

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1170774	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Hyperuricemic nephropathy, familial juvenile type 4; Thyroid cancer, nonmedullary, 1; Nonpapillary renal cell carcinoma; Ovarian serous cystadenocarcinoma; Malignant tumor of esophagus; Cervical cancer	germline	6	Jan 19, 2026	clinvar