Variant · Snv
GUCY2C NM_004963.4(GUCY2C):c.1798-3C>A
CI-VAR-00196256Explore in graph →NM_004963.4:c.1798-3C>AClinVar 1170630 rs7966185
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1170630 | Benign | criteria provided, multiple submitters, no conflicts | 2 | GUCY2C-related disorder; Uterine corpus endometrial carcinoma; Gastric cancer; Lung cancer; Ovarian serous cystadenocarcinoma; Clear cell carcinoma of kidney; Colon adenocarcinoma; Colorectal cancer; Sarcoma | germline | 6 | Feb 03, 2026 | clinvar |