Variant · Snv
TCF3 NM_003200.5(TCF3):c.1308C>T (p.Gly436=)
CI-VAR-00196411Explore in graph →p.Gly436=NM_003200.5:c.1308C>TClinVar 1169440 rs1140828
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1169440 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Malignant lymphoma, large B-cell, diffuse; Uveal melanoma; Colon adenocarcinoma; Colorectal cancer; Uterine carcinosarcoma; Adrenocortical carcinoma, hereditary | germline | 7 | Feb 04, 2026 | clinvar |