Variant · Snv
ARHGEF18 NM_001367823.1(ARHGEF18):c.1773C>T (p.Gly591=)
CI-VAR-00196419Explore in graph →p.Gly591=NM_001367823.1:c.1773C>TClinVar 1168288 rs117706799
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1168288 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Melanoma; Hepatocellular carcinoma; Colon adenocarcinoma; Sarcoma; Malignant tumor of esophagus; Adrenocortical carcinoma, hereditary; Cervical cancer | germline | 3 | Feb 01, 2026 | clinvar |