Variant · Snv
MAP3K14 NM_003954.5(MAP3K14):c.327-7G>T
CI-VAR-00196356Explore in graph →NM_003954.5:c.327-7G>TClinVar 1166450 rs17846855
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1166450 | Benign | criteria provided, multiple submitters, no conflicts | 2 | NIK deficiency; MAP3K14-related disorder; Hepatocellular carcinoma; Uterine corpus endometrial carcinoma; Uveal melanoma; Malignant lymphoma, large B-cell, diffuse; Ovarian serous cystadenocarcinoma; Thymoma; Acute myeloid leukemia | germline | 5 | Feb 04, 2026 | clinvar |