Variant · Snv
DCLRE1C NM_001033855.3(DCLRE1C):c.781-17C>G
CI-VAR-00196219Explore in graph →NM_001033855.3:c.781-17C>GClinVar 1166419 rs41298886
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1166419 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Severe combined immunodeficiency due to DCLRE1C deficiency; Malignant lymphoma, large B-cell, diffuse; Uterine carcinosarcoma; Uterine corpus endometrial carcinoma; Gastric cancer; Thymoma; Acute myeloid leukemia | germline | 4 | Feb 04, 2026 | clinvar |