Variant · Snv
COL27A1 NM_032888.4(COL27A1):c.3888G>A (p.Pro1296=)
CI-VAR-00196198Explore in graph →p.Pro1296=NM_032888.4:c.3888G>AClinVar 1165562 rs113772516
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1165562 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Colorectal cancer; Thyroid cancer, nonmedullary, 1; Cholangiocarcinoma; Colon adenocarcinoma; Melanoma; Malignant tumor of esophagus; Sarcoma; Gastric cancer; Uterine carcinosarcoma; Thymoma; Adrenocortical carcinoma, hereditary; Lung cancer; Cervical cancer | germline | 3 | Feb 04, 2026 | clinvar |