GUCY2C NM_004963.4(GUCY2C):c.612-16C>A

CI-VAR-00196258Explore in graph →NM_004963.4:c.612-16C>AClinVar 1165268 rs58911033

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1165268	Benign	criteria provided, multiple submitters, no conflicts	2	Congenital diarrhea 6; Intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency; Uterine carcinosarcoma	germline	4	Feb 04, 2026	clinvar