Variant · Snv
FAT1 NM_005245.4(FAT1):c.12653A>G (p.Asp4218Gly)
CI-VAR-00179554Explore in graph →p.Asp4218GlyNM_005245.4:c.12653A>GClinVar 1050539 rs72716244
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1050539 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Clear cell carcinoma of kidney; Uveal melanoma; Nonpapillary renal cell carcinoma; Sarcoma; Hepatocellular carcinoma; Thyroid cancer, nonmedullary, 1; Malignant tumor of esophagus | germline | 7 | Feb 01, 2026 | clinvar |