NLRP1 NM_033004.4(NLRP1):c.439C>T (p.Arg147Cys)

CI-VAR-00175907Explore in graph →p.Arg147CysNM_033004.4:c.439C>TClinVar 1016715 rs147371989

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1016715	Uncertain significance	criteria provided, multiple submitters, no conflicts	2	Corneal intraepithelial dyskeratosis-palmoplantar hyperkeratosis-laryngeal dyskeratosis syndrome; Autoinflammation with arthritis and dyskeratosis; Vitiligo-associated multiple autoimmune disease susceptibility 1; Respiratory papillomatosis, juvenile recurrent, congenital	germline	3	Oct 25, 2025	clinvar